中国中药杂志

2022, v.47(10) 2584-2596

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近五年三七化学成分、色谱分析、三七提取物和药理活性的研究进展
Panax notoginseng: a review on chemical components, chromatographic analysis, P. notoginseng extracts, and pharmacology in recent five years

黄依丹;成嘉欣;石颖;高智慧;胡玉莹;康荣;王莹;刘越;马双成;
HUANG Yi-dan;CHENG Jia-xin;SHI Ying;GAO Zhi-hui;HU Yu-ying;KANG Rong;WANG Ying;LIU Yue;MA Shuang-cheng;School of Chinese Materia Medica, Beijing University of Chinese Medicine;National Institutes for Food and Drug Control;

摘要(Abstract):

三七作为一种名贵中药材在我国具有悠久的使用历史,由于其在保护心脑血管系统、保护神经系统和肿瘤抑制等方面具有较强的药理活性而受到研究人员的高度关注。近年来,随着三七研究思路、技术方法以及科研设备的发展,对三七开展了广泛而深入的研究并取得了丰硕的成果。该文对近五年三七相关领域研究进行综述,主要从化学成分、色谱分析、三七提取物以及药理作用等4个方面进行总结和整理,其中三七提取物应用于质量控制研究等内容系首次归纳。综上,该研究为三七的质量控制、产品开发及临床合理应用等提供理论依据。
As a famous and precious Chinese medicinal material, Panax notoginseng(PN) has been commonly used for a long history in China. As reported, PN exhibits significant pharmacological actions in protecting cardiocerebral vascular system and nervous system and suppressing tumors. In recent years, with the innovation in ideas, as well as the development of methods and equipment, PN has been extensively investigated, and notable progress has been made. This paper reviewed the advancements of PN in recent five years from chemical components, chromatographic analysis, P. notoginseng extracts, and pharmacology, in which the application of PN extracts in quality control was first summarized. The present study aims to provide a theoretical basis for quality control, product development, and rational medication of PN.

关键词(KeyWords): 三七;化学成分;色谱分析;三七提取物;质量控制;药理作用
Panax notoginseng;chemical components;chromatographic analysis;Panax notoginseng extracts;quality control;pharmacological activities

Abstract:

Keywords:

基金项目(Foundation): 国家药典委员会药品标准制修订研究课题(2020Z09);; 国家“重大新药创制”科技重大专项(2018ZX09735-006)

作者(Authors): 黄依丹;成嘉欣;石颖;高智慧;胡玉莹;康荣;王莹;刘越;马双成;
HUANG Yi-dan;CHENG Jia-xin;SHI Ying;GAO Zhi-hui;HU Yu-ying;KANG Rong;WANG Ying;LIU Yue;MA Shuang-cheng;School of Chinese Materia Medica, Beijing University of Chinese Medicine;National Institutes for Food and Drug Control;

DOI: 10.19540/j.cnki.cjcmm.20211220.202

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