中国中药杂志

2012, v.37(08) 1072-1075

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生物信息学在中药材分子鉴别中的应用
Application of bioinformatics in molecular authentication of traditional Chinese medicinal materials

黄家乐;邵鹏柱;
WONG Kalok1,SHAW Pangchui1,2(1.State Key Laboratory of Phytochemistry and Plant Resources in West China(CUHK), Institute of Chinese Medicine,The Chinese University of Hong Kong,Hong Kong,China; 2.School of Life Science,The Chinese University of Hong Kong,Hong Kong,China)

摘要(Abstract):

随着DNA技术鉴定中药材日渐普及,相关研究资料与日俱增,研究人员必需掌握生物信息学知识作有效序列信息搜集和分析。文章综述了生物信息学在DNA鉴定中药材的应用范围,包括查找物种分类条目、下载DNA序列数据、比对数据库序列、多重序列排序、及序列分析等。除逐一介绍外,也指出当中应注意事项。
Benefiting from various DNA technologies,DNA markers have now become a popular means for the identification of Chinese medicinal materials.Facing the huge amount of valuable data that has been produced,researchers need to understand the bioinformatics tools for analyzing the obtained DNA information.This paper summarizes the applications of bioinformatics in molecular authentication of Chinese medicinal materials,including checking phylogenetic information of the samples,searching and retrieving DNA sequence data,matching of similarity between the sequences and performing multiple sequence alignment.

关键词(KeyWords): 中药材;鉴定;生物信息学
Chinese medicinal materials;authentication;bioinformatics

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作者(Author): 黄家乐;邵鹏柱;
WONG Kalok1,SHAW Pangchui1,2(1.State Key Laboratory of Phytochemistry and Plant Resources in West China(CUHK), Institute of Chinese Medicine,The Chinese University of Hong Kong,Hong Kong,China; 2.School of Life Science,The Chinese University of Hong Kong,Hong Kong,China)

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