中国中药杂志

2018, v.43(02) 267-273

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分子印迹技术及其在萜类化合物中的应用
Molecular imprinting technology and its application in terpenoids

梁宇岚;杨鑫;潘玲玲;吴亚芬;李斐;万娜;周翔;刘波;李斌;
LIANG Yu-lan;YANG Xin;PAN Ling-ling;WU Ya-fen;LI Fei;WAN Na;ZHOU Xiang;LIU Bo;LI Bin;Pharmacy College,Jiangxi University of Traditional Chinese Medicine;School of Chemical and Technology,Harbin Institute of Technology;

摘要(Abstract):

分子印迹技术以其高选择性、特异识别性等特点,在黄酮、生物碱、多酚类等化合物的分离分析中广泛应用,但是其在萜类化合物中的应用研究较少。该文通过文献调研统计,系统探讨功能单体、交联剂和致孔剂等常见合成元素对聚合物性能的影响,重点对萜类分子印迹技术在固相萃取、传感器、膜分离、色谱分离等方面的研究进行了总结,并分析目前该技术存在的缺点和改进方向,为更好将分子印迹技术应用于萜类化合物分离分析提供参考。
Molecular imprinting technology is widely used in the separation and analysis of compounds such as flavonoids,alkaloids and polyphenols,due to its high selectivity and specific recognition and so on. However,no much of attention has been paid to the terpenoids. This paper is aimed to not only review the effects of common synthetic elements such as functional monomers,cross-linking agents and porogens on the polymer properties,but also highlight the application of terpene molecular imprinting in solid phase extraction,sensor,membrane separation and chromatographic separation by means of statistical analysis of literature. Furthermore,the shortcomings and improvement directions are discussed. We believed that this paper could provide references for better applications of molecular imprinting techniques to the analysis of terpenoid compounds.

关键词(KeyWords): 分子印迹技术;萜类化合物;应用
molecular imprinting technology;terpenoids;application

Abstract:

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基金项目(Foundation): 国家自然科学基金项目(81760708);; 江西省主要学科学术和技术带头人资助计划项目(20162BCB22016);; 江西省教育厅重点项目(GJJ160809)

作者(Author): 梁宇岚;杨鑫;潘玲玲;吴亚芬;李斐;万娜;周翔;刘波;李斌;
LIANG Yu-lan;YANG Xin;PAN Ling-ling;WU Ya-fen;LI Fei;WAN Na;ZHOU Xiang;LIU Bo;LI Bin;Pharmacy College,Jiangxi University of Traditional Chinese Medicine;School of Chemical and Technology,Harbin Institute of Technology;

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