中国中药杂志

2010, v.35(06) 718-721

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野菊花的化学成分研究
Chemical constituents from flowers of Chrysanthemum indicum

王锦越;陈东;梁丽娟;薛培凤;屠鹏飞;
WANG Jinyue1,2,CHEN Dong2,LIANG Lijuan2,XUE Peifeng1,TU Pengfei1,2*(1.School of Pharmaceutical Sciences,Inner Mongolia Medical College,Hohhot 010059,China;2.State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100191,China)

摘要(Abstract):

目的:研究菊科植物野菊花的化学成分。方法:利用各种色谱技术进行分离,现代波谱技术鉴定化合物结构。结果:从野菊花中分离得到12个化合物,分别鉴定为金合欢素(1),麦黄酮(2),2′,4′-二羟基查尔酮(3),5-羟基-4′,7-甲氧基黄酮(4),7-羟基二氢黄酮(5),异鼠李黄素(6),5,6,7-三羟基-3′,4′,5′-三甲氧基黄酮(7),槲皮素(8),(3β,5α,6β,7β,14β)-eudesmen-3,5,6,11-tetrol(9),丁香脂素(10),鹅掌楸碱(11),5,4′-二羟基-7-甲氧基黄酮(12)。结论:化合物37,107,1012均为首次从该种植物中分离得到,3,5,7,10,11为首次从该属植物中分离得到。
Objective:To investigate the chemical constituents of the flowers of Chrysanthemum indicum.Method: The chemical constituents were isolated by various column chromatographic methods.The structures were identified by spectral data.Result: Twelve compounds were isolated and identified as acacetin(1),tricin(2),2′,4′-dihydroxychalcone(3),5-hydroxy-4′,7-dimethoxyflavon(4),7-hydroxyflavonone(5),isorhamnetin(6),5,6,7-trihydroxy-3′,4′,5′-trimethoxyflanon(7),quercetin(8),(3β,5α,6β,7β,14β)-eudesmen-3,5,6,11-tetrol(9),syringaresinol(10),liriodendrin(11),and genkwanin(12).Conclusion: Compounds 3-7,10-12 were isolated from this species for the first time,and compounds 3,5,7,10,11 were obtained from genus Chrysanthemum for the first time.

关键词(KeyWords): 野菊花;菊属;化学成分;黄酮;倍半萜
Chrysanthemum indicum;Chrysanthemum;chemical constituents;flavonoids;sesquiterpenes

Abstract:

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作者(Authors): 王锦越;陈东;梁丽娟;薛培凤;屠鹏飞;
WANG Jinyue1,2,CHEN Dong2,LIANG Lijuan2,XUE Peifeng1,TU Pengfei1,2*(1.School of Pharmaceutical Sciences,Inner Mongolia Medical College,Hohhot 010059,China;2.State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100191,China)

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