中国中药杂志

2008, (18) 2070-2073

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牡丹皮不同部位有效成分含量测定及指纹图谱化学成分研究
Studies on content determination and fingerprint of active constituents in different parts of cortex moutan

周刚;吕庆红;
ZHOU Gang,LV Qing-hong (1.Center for Drug Evaluation,State Food and Drug Administration,Beijing 100038,China;2.First Affiliated Hospital,Henan Traditional Chinese Medicine College,Zhengzhou 450000,China)

摘要(Abstract):

目的:对牡丹皮不同部位进行化学成分研究,为牡丹皮的最佳产地加工方法提供依据。方法:采用高效液相色谱法,测定牡丹皮各部位中丹皮酚、芍药苷的含量,并进行指纹图谱分析。结果:栓皮部与韧皮部比较,其丹皮酚的含量约高出1倍,木心部中的含量接近韧皮部的1/2;栓皮部与韧皮部比较,其芍药苷的含量约高出3.5倍,木心部中的含量约高出韧皮部的1倍;指纹图谱中,韧皮部中有效成分的含量较高。结论:产地加工时可以不去皮而只去心,既能简化产地加工的繁琐程序又能提高样品中有效成分的含量。
Objective: To determine the chemical constituents in different parts of Cortex Moutan,which can provides evidences to the processing techniques of Cortex Moutan.Method: The contents of paeonol,peoniflorin and fingerprints in different parts of Cortex Moutan were determined by HPLC.Result: Compareed with phloem,paeonol in cork is twice as many,but paeonol in duramen is half as many peoniflorin in cork is half and four times as many,peoniflorin in duramen is twice as many,the contents of active ingredients in duramen are high in fingerprint.Conclusion: If we only abandon the core,then we may get simple processings with the active ingredient contents increasing.

关键词(KeyWords): 牡丹皮;不同部位;化学成分;产地加工
Cortex Moutan;differernt parts;chemical constituents;processing techniques

Abstract:

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基金项目(Foundation): 河南省重大科技攻关项目(0422030700)

作者(Author): 周刚;吕庆红;
ZHOU Gang,LV Qing-hong (1.Center for Drug Evaluation,State Food and Drug Administration,Beijing 100038,China;2.First Affiliated Hospital,Henan Traditional Chinese Medicine College,Zhengzhou 450000,China)

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