中国中药杂志

2021, v.46(06) 1333-1338

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黄芪的发酵研究进展
Research progress of Astragali Radix fermentation

董凡;李浩然;王少平;杨爱琳;王喻淇;刘子菡;代龙;张加余;
DONG Fan;LI Hao-ran;WANG Shao-ping;YANG Ai-lin;WANG Yu-qi;LIU Zi-han;DAI Long;ZHANG Jia-yu;School of Pharmacy,Bin Zhou Medical University;School of Chinese Pharmacy,Beijing University of Chinese Medicine;School of Pharmacy,Shandong University of Traditional Chinese Medicine;

摘要(Abstract):

黄芪是最常用的补气类中药之一,具有益气固表、利尿消肿、托毒生肌等功效。近年来,中药发酵受到广泛关注。在传统中药发酵技术基础上发展起来的现代中药发酵技术,将中药发酵与现代生物技术相结合,可进一步提高中药的药用价值,具有广阔的发展前景。该文从发酵菌种、发酵形式、工艺优化、物质基础及药理作用变化和应用研究等方面对黄芪发酵的相关进展进行了综述,以期为黄芪的后续研究和开发利用提供参考。
Astragali Radix is one of traditional Chinese medicines with effects in invigorating Qi for consolidating superficies, inducing diuresis to alleviate edema, promoting pus discharge and tissue regeneration. In recent years, the traditional Chinese medicine fermentation technology has received extensive attentions due to its high efficiency and safety. The pharmacological functions of traditional Chinese medicines could be further enhanced after microbial fermentation, which has a broad development prospects. In this paper, we summarized relevant literatures of Astragali Radix fermentation in such aspects as fermentation strains, fermentation forms, process optimization, active ingredients and pharmacological effects, in the expectation of providing a reference for development and utilization of Astragali Radix.

关键词(KeyWords): 黄芪;发酵;菌种;药理作用
Astragali Radix;fermentation;strain;pharmacological effect

Abstract:

Keywords:

基金项目(Foundation): 山东省青创人才引育计划项目(10073004);; 滨州医学院科研启动项目(BY2019KYQD05,BY2019KYQD06);; 中药大健康产业化平台项目(2019XDRHXMPT18);; 中央财政部名贵中药资源可持续利用能力建设项目(2060302-1907-08)

作者(Author): 董凡;李浩然;王少平;杨爱琳;王喻淇;刘子菡;代龙;张加余;
DONG Fan;LI Hao-ran;WANG Shao-ping;YANG Ai-lin;WANG Yu-qi;LIU Zi-han;DAI Long;ZHANG Jia-yu;School of Pharmacy,Bin Zhou Medical University;School of Chinese Pharmacy,Beijing University of Chinese Medicine;School of Pharmacy,Shandong University of Traditional Chinese Medicine;

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DOI: 10.19540/j.cnki.cjcmm.20201207.602

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