龙选宁;韩凤;韦琳;孟凡成;屈珅玥;陈敏;
LONG Xuan-ning;HAN Feng;WEI Lin;MENG Fan-cheng;QU Shen-yue;CHEN Min;College of Pharmaceutical Sciences, Southwest University;Chongqing Institute of Medical Plant Cultivation;

• 1:西南大学药学院
• 2:重庆市药物种植研究所

摘要(Abstract)：

运用正、反相硅胶色谱柱、Sephadex LH-20、MCI及半制备高效液相色谱对毛黄堇乙酸乙酯部位进行化学成分分离和纯化,通过波谱学分析方法,结合文献数据,从毛黄堇乙酸乙酯部位鉴定了18个单体化合物,包括17个已知生物碱和1个萜类,其中化合物1(tomentellaine A)为生物碱类新化合物,化合物2～5、7～14、16～18为首次从该植物中分离得到。
The chemical constituents in the ethyl acetate extract of Corydalis tomentella was isolated and purified with normal and reversed phase silica gel column chromatography, Sephadex LH-20, MCI, and semi-preparative HPLC. The compound structures were identified based on spectroscopic experiments and reported papers. Finally, eighteen compounds(1-18) were obtained from C. tomentella, including 17 alkaloids and 1 terpenoid. Among them, compound 1(tomentellaine A) was a novel alkaloid. Compounds 2-5, 7-14, and 16-18 were isolated from this plant for the first time.

关键词(KeyWords)： 毛黄堇;生物碱;化学成分
Corydalis tomentella;alkaloid;chemical constituent

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 龙选宁;韩凤;韦琳;孟凡成;屈珅玥;陈敏;
LONG Xuan-ning;HAN Feng;WEI Lin;MENG Fan-cheng;QU Shen-yue;CHEN Min;College of Pharmaceutical Sciences, Southwest University;Chongqing Institute of Medical Plant Cultivation;

DOI: 10.19540/j.cnki.cjcmm.20210706.201

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