中国中药杂志

2010, v.35(07) 847-851

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中药浸膏粉吸湿过程模型及应用研究
Study on moisture sorption process model and application traditional Chinese medicine extract powder

林婷婷;何雁;肖雄;袁亮;饶小勇;罗晓健;
LIN Tingting,HE Yan,XIAO Xiong,YUAN Liang,RAO Xiaoyong,LUO Xiaojian,(1.National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal MedicineJiangxi University of Traditional Chinese Medicine,Nanchang 330006,China)

摘要(Abstract):

目的:研究中药浸膏粉的吸湿过程特点,建立数学模型,为深入研究中药浸膏吸湿行为提供一种新的方法,为确定生产周期、预测产品稳定性提供参考。方法:分析中药浸膏粉吸湿过程,应用物质质量守恒定律、费克扩散第一定律,建立双指数吸湿过程模型,对中药浸膏吸湿数据进行拟合,并与其他常用5种模型比较,评价双指数模型的效果。结果:经统计分析可知,双指数模型、Weibull分布模型、一级过程模型的决定系数(R2)均较大,残差平方和(RSS),AIC值均较小,综合3种模型的实际应用意义,认为双指数模型更适用于模拟中药浸膏粉的吸湿过程。结论:所建立的双指数模型适合表征中药浸膏粉的吸湿过程。
Objective: Study on the moisture sorption process characteristics of traditional Chinese medicine extract powder,to establish a mathematical model,provide a new method for in-depth study for moisture sorption behavior of traditional Chinese medicine extract powder and a reference for determine the production cycle,and predict product stability.Method: Analyzed moisture absorption process of traditional Chinese medicine extract powder by utilized the law of conservation of mass and Fick's first law to establish the double exponential absorption model,fitted the moisture absorption data and compared with other commonly used five kinds of model to estimate the double-exponential absorption model.Result: The statistical analysis showed that the coefficient of determination(R2)of double exponential model,Weibull distribution model and first order kinetics model were large,but the residues sum of squares(RSS)and AIC values were small.Synthesized the practical application meaning,we consided that the double exponential model was more suitable for simulating the process of Chinese medicine extract powder moisture absorption.Conclusion: The double exponential is suitable for characterization the process of traditional Chinese medicine extract moisture absorption.

关键词(KeyWords): 中药浸膏粉;吸湿过程;数学模型
traditional Chinese medicine;moisture absorption process;mathematical model

Abstract:

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基金项目(Foundation): 国家自然科学基金项目(30860382)

作者(Author): 林婷婷;何雁;肖雄;袁亮;饶小勇;罗晓健;
LIN Tingting,HE Yan,XIAO Xiong,YUAN Liang,RAO Xiaoyong,LUO Xiaojian,(1.National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal MedicineJiangxi University of Traditional Chinese Medicine,Nanchang 330006,China)

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