中国中药杂志

2012, v.37(21) 3203-3207

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黄芪中有效成分药理活性的研究进展
Chemical composition and pharmacological activities of Astragali Radix

张蔷;高文远;满淑丽;
ZHANG Qiang1,2,GAO Wen-yuan1,MAN Shu-li1(1.School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China; 2.Tianjin Medical University General Hospital Institute of Geriatrics,Tianjin 300072,China)

摘要(Abstract):

黄芪药用历史悠久,古有"补药之长"之称,为历代中医最常用的中药之一。近年来,国内外学者对黄芪的化学组成、药理活性进行了较为广泛的研究。成分分析表明,黄芪以多糖、三萜、黄酮等成分为主;药理实验及临床报道表明,黄芪在免疫调节、抗肿瘤、抗病毒、糖尿病、延缓衰老等方面具有重要作用。因此,对黄芪的各个有效成分的活性总结具有临床指示性意义。该文通过文献综述,总结了黄芪不同活性成分的药理活性及作用机制,为该药临床研究提供理论依据,进而为其开发利用提供依据。
Astragali Radix,as a tonic with a long history,is one of the most common traditional Chinese medicines.Recently,chemical composition and pharmacological activities of Astragali Radix have been widely reported.Polysaccharide,triterpenes and flavonoids are regarded to its effective components.Pharmacological experiments and clinical reports show that Astragali Radix has good effects on immune-regulation,anti-tumor,anti-virus,diabetes,anti-aging and so on.Therefore,it shows a good prospect to make good use of its effective components.

关键词(KeyWords): 黄芪;多糖;三萜;黄酮
Astragali Radix;active ingredient;pharmacological activities;polysaccharides;triterpenes

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基金项目(Foundation): 天津市自然科学基金项目(10JCYBJC25800);; 天津医科大学基金资助项目(2009KY17);;

作者(Author): 张蔷;高文远;满淑丽;
ZHANG Qiang1,2,GAO Wen-yuan1,MAN Shu-li1(1.School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China; 2.Tianjin Medical University General Hospital Institute of Geriatrics,Tianjin 300072,China)

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