中国中药杂志

1988, (08) 39-41+63

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红芪建中汤、四君子汤对大黄合剂复制小鼠“脾虚”模型的影响
Effect of Hongqi Jianzhong Decoction and Sijunzi Decoction on Mouse Model of Deficiency in the Spleen Caused by Dahuang Mixture

吴爱光,孙启祥,郑云霞,黄正良
Wu Aiguang, Sun Qixiang, Zheng Yunxia and Huang Zhengliang (Gansu College of Traditional Chinese Medicine, Lanzhou)

摘要(Abstract):

用大黄合剂(大黄、芒硝)可复制出“脾虚”模型,表现为粪便稀薄、行动迟缓、被毛蓬松、消瘦弓背、体重减轻、体温下降、摄食减少、血液微循环障碍。部分免疫指标变化不大。红芪建中汤、四君子汤可促进“脾虚”小鼠复健,并加速其微循环的改善。
It has been found that an animal model having deficiency in the spleen can be established by treating mouse with Dahuang mixture (Rhubarb, Mirabilite) intragastrically. The symptoms of the mouse include: loose stool, sluggishness, looseness of the hair, thin and bent back, loss of weight, lower temperature, indigestion and anorexia, and hypofunction of microcirculation of blood, etc.. Compared with healthy mouse, the ill mouse treated with Hongqi Jianzhong decoction or Sijunzi decoction has only little change in part of immunological indexes, and will recover faster than that without any treatment.

关键词(KeyWords): 红芪建中汤;四君子汤;大黄合剂;“脾虚”模型;微循环
Hongqi Jianzhong decoction; Sijunzi decoction; Dahuang mixture; animal model with spleen deficiency; microcirculation of blood

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作者(Author): 吴爱光,孙启祥,郑云霞,黄正良
Wu Aiguang, Sun Qixiang, Zheng Yunxia and Huang Zhengliang (Gansu College of Traditional Chinese Medicine, Lanzhou)

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