中国中药杂志

2015, v.40(23) 4545-4551

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

微波消解ICP-MS同时测定玛咖中27种元素
Determination of 27 elements in Maca nationality's medicine by microwave digestion ICP-MS

于桂芳;仲海洁;胡军华;王婧;黄文哲;王振中;萧伟;
YU Gui-fang;ZHONG Hai-jie;HU Jun-hua;WANG Jing;HUANG Wen-zhe;WANG Zhen-zhong;XIAO Wei;Jangsu Kanion Pharmaceutical Co.,Ltd.;State Key Laberatory of New-tech for Chinese Medicine Pharmaceutical Process;

摘要(Abstract):

该文建立了用微波消解-电感耦合等离子体质谱仪(ICP-MS)同时分析玛咖中锂(Li),铍(Be),硼(B),镁(Mg),铝(Al),钪(Sc),钛(Ti),钒(V),铬(Cr),锰(Mn),铁(Fe),钴(Co),镍(Ni),铜(Cu),锌(Zn),镓(Ga),砷(As),锶(Sr),钼(Mo),镉(Cd),锡(Sn),锑(Sb),钡(Ba),镧(La),汞(Hg),铅(Pb),铋(Bi)共27种元素的方法。样品经微波消解后,利用ICP-MS测定上述元素,以内标法改善基体效应及干扰,通过标准曲线计算含量。实验结果表明所有元素的线性关系良好,相关系数(r)为0.999 4~1.000 0(Hg为0.998 2);检出限为0.003~2.662μg·L~(1);重复性的相对标准偏差(RSD)大多数小于5%(个别元素除外);加样回收率为78.5%~123.7%,RSD大多数小于5%(个别元素除外);标准物质中27个元素的测定值基本都在标准值范围内(个别元素除外)。该方法灵敏度高,专属性好,重复性好,分析速度快,适用于玛咖中多种元素的含量测定,为玛咖的质量控制提供参考依据。
An analysis method has been established to test 27 elements( Li,Be,B,Mg,Al,Sc,Ti,V,Cr,Mn,Fe,Co,Ni,Cu,Zn,Ga,As,Sr,Mo,Cd,Sn,Sb,Ba,La,Hg,Pb,Bi) in Maca nationality's medicine with microwave digestion-ICP-MS. Sample solutions were analyzed by ICP-MS after microwave digestion,and the contents of elements were calculated according to their calibration curves,and internal standard method was adopted to reduce matrix effect and other interference effects. The experimental results showed that the linear relations of all the elements were very good; the correlation coefficient( r) was 0. 999 4-1. 000 0( Hg was 0. 998 2); the limits of detection were 0. 003-2. 662 μg·L~(1); the relative standard deviations for all elements of reproducibility were lower than 5%( except the individual elements); the recovery rate were 78. 5%-123. 7% with RSD lower than 5%( except the individual elements). The analytical results of standard material showed acceptable agreement with the certified values. This method was applicable to determinate the contents of multi-elements in Maca which had a high sensitivity,good specificity and good repeatability,and provide basis for the quality control of Maca.

关键词(KeyWords): 玛咖;电感耦合等离子质谱;微波消解;元素分析
Maca;ICP-MS;microwave digestion;element analysis

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 于桂芳;仲海洁;胡军华;王婧;黄文哲;王振中;萧伟;
YU Gui-fang;ZHONG Hai-jie;HU Jun-hua;WANG Jing;HUANG Wen-zhe;WANG Zhen-zhong;XIAO Wei;Jangsu Kanion Pharmaceutical Co.,Ltd.;State Key Laberatory of New-tech for Chinese Medicine Pharmaceutical Process;

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享