中国中药杂志

1996, (02)

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山大黄消炎止血胶囊药代动力学参数测定
Determination of Pharmacokinetic Parameters of Shandahuang Xiaoyan Zhixue Capsules

梁资富,刘玉玲,门泉渌,吕燕萍,苑伟,宋京都,朱喜春
Liang Zifu,Liu Yuling,Men Quanlu,Lu Yanpin,Yuan Wei,Song Jingdu and Zhu Xichi (Gansu Provincial Institute for Drug Control,Lanzhou 730000)

摘要(Abstract):

根据药物累计法与药理效应法原理,分别以动物死亡为指标,测出山大黄消炎止血胶囊在不同时间的体存率及毒代、药代动力学参数。
Based on residual accumulation and biophase availabilty principles and using animal death rate as index,determination has been carried out of the residual accumulation rate as well as the toxicokinetic and pharmacokinetic parameters at different times of the Shandahuang Xiaoyan Zhixue Capsules.

关键词(KeyWords): 药代动力学参数,毒代动力学参数,止血,剂量
pharmacokinetic parameters;toxicokinetic parameters;hemostasis;administration and dosage (original article on page 95)

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作者(Author): 梁资富,刘玉玲,门泉渌,吕燕萍,苑伟,宋京都,朱喜春
Liang Zifu,Liu Yuling,Men Quanlu,Lu Yanpin,Yuan Wei,Song Jingdu and Zhu Xichi (Gansu Provincial Institute for Drug Control,Lanzhou 730000)

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