中国中药杂志

2019, v.44(24) 5287-5290

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芪龙胶囊临床应用专家共识
Experts consensus statement on Qilong Capsules in clinical practice

王志飞;谢颖桢;谢雁鸣;赵德喜;王敏忠;于海青;曹晓岚;李博;
WANG Zhi-fei;XIE Ying-zhen;XIE Yan-ming;ZHAO De-xi;WANG Min-zhong;YU Hai-qing;CAO Xiao-lan;LI Bo;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences;Dongzhimen Hospital,Beijing University of Chinese Medicine;Affiliated Hospital of Changchun University of Traditional Chinese Medicine;Shandong Provincial Hospital;Taiyuan Hospital of Traditional Chinese Medicine;Affiliated Hospital of Shandong University of Traditional Chinese Medicine;Beijing Hospital of Trad

摘要(Abstract):

芪龙胶囊是中医药补气活血理论的代表药物,临床应用具有鲜明的中医特色;其适应症缺血性中风(脑梗死)病情复杂、病理环节众多,各阶段的治疗原则和方法也有不同,如果药物的介入时机、使用剂量、用药疗程等不合适,不仅难以充分发挥疗效,还有可能引发出血等不良反应。为进一步提高临床医生对芪龙胶囊的认识,更好地指导临床合理用药,项目组邀请了来自全国相关领域的临床一线专家、药学专家和循证医学方法学专家编写该共识。该共识采取临床研究证据和专家经验相结合的方式,对于有研究证据支持的临床问题形成推荐意见,对于没有证据支持的临床问题形成共识建议。该共识推荐了芪龙胶囊临床应用的人群特点、介入时机、剂量、疗程、合并用药及使用禁忌,并介绍了其安全性特征,以指导中医、西医和中西医结合医生应用芪龙胶囊治疗脑梗死的临床实践。
Qilong Capsules is the representative Chinese patent medicine of the theory of " invigorating Qi and activating blood circulation" in traditional Chinese medicine( TCM),with distinct characteristics of TCM in clinical application. Qilong Capsules indication on package insert is ischemic stroke( cerebral infarction),which is a complex disease and has many pathological links. The treatment principles and methods at various stages are different. Inappropriate time of intervention,dosage and course of treatment make it difficult to give full play to the efficacy,but also cause adverse reactions,such as bleeding. In order to promote the rational use of Qilong Capsules,the project team invited frontline clinical experts,pharmaceutical experts and methodologist of evidence-based medicine around China to develop the consensus. The consensus is based on a combination of clinical research evidence and expert experi-ence to give recommendations for clinical problems with evidence support and expert consensus suggestions for clinical problems without evidence support. The consensus recommends the indication,timing of intervention,dosage,course of treatment,combined medication and contraindications of Qilong Capsules in clinical application,and introduced its safety characteristics,in order to guide clinical medical workers( involving Chinese medicine,Western medicine,combining traditional Chinese and Western medicine) to use Qilong Capsules reasonably in the treatment of cerebral infarction.

关键词(KeyWords): 芪龙胶囊;专家共识;推荐意见;证据分级;临床应用
Qilong Capsules;expert consensus statement;recommendation;classification of evidence;clinical practice

Abstract:

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基金项目(Foundation): 国家重点研发计划项目(2018YFC1707400,2018YFC1707410);; 2015中医药行业专项(201507003-8)

作者(Author): 王志飞;谢颖桢;谢雁鸣;赵德喜;王敏忠;于海青;曹晓岚;李博;
WANG Zhi-fei;XIE Ying-zhen;XIE Yan-ming;ZHAO De-xi;WANG Min-zhong;YU Hai-qing;CAO Xiao-lan;LI Bo;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences;Dongzhimen Hospital,Beijing University of Chinese Medicine;Affiliated Hospital of Changchun University of Traditional Chinese Medicine;Shandong Provincial Hospital;Taiyuan Hospital of Traditional Chinese Medicine;Affiliated Hospital of Shandong University of Traditional Chinese Medicine;Beijing Hospital of Trad

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