中国中药杂志

2020, v.45(14) 3481-3488

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外来植物药朝鲜蓟文献研究及其“中药化”理论探讨
Study on literature of artichoke and properties of traditional Chinese medicine

赵艺萌;王禅缔;张睿;侯新娟;赵凡;张建军;王淳;
ZHAO Yi-meng;WANG Chan-di;ZHANG Rui;HOU Xin-juan;ZHAO Fan;ZHANG Jian-jun;WANG Chun;College of Traditional Chinese Medicine, Beijing University of Chinese Medicine;Beijing Institute of Clinical Pharmacy;

摘要(Abstract):

该研究通过对外来植物药朝鲜蓟Cynara scolymus的国内外相关文献进行全面查阅,从传统中医药理论角度对朝鲜蓟的中药性能及其功用进行探讨,使朝鲜蓟实现"中药化",为其临床应用与合理配伍提供理论依据。以PubMed、Web of Science、EMbase、Cochrane Library及中国知网(CNKI)、万方、中文科技期刊全文数据库、中国生物医学文献数据库为文献来源,筛选其中与朝鲜蓟相关的可信度较高的文献,将所得文献根据临床应用、化学成分、药理作用、毒副作用等方面进行系统化归类,并结合传统中医理论进行分析,推导得出:朝鲜蓟,味苦,微寒,归脾、胃、肝、胆经。功能消积导滞,理气和胃,清利湿热,化浊降脂。用于消化不良,食少纳呆,呕恶腹胀,胁痛黄疸,高脂血症等。通过对朝鲜蓟的相关文献进行分析研究,使其"中药化",赋予其中药性能与功用,为进一步开展动物实验及临床研究提供理论基础。外来植物药"中药化"的研究模式,可为世界各地植物药的引进及研究提供借鉴,可在极大程度上丰富我国中药资源,并对促进中医药的可持续发展具有重要意义。
In this article, the foreign and domestic literature on alien plant medicine Cynara scolymus was reviewed to explore its properties and functions in traditional Chinese medicine theory, and provide theoretical basis for clinical application and reasonable compatibility. Based on the literature databases of PubMed, Web of Science, Embase, the Cochrane Library, CNKI, VIP and Sinomed, the articles with high reliability related to C. scolymus were screened out and the obtained articles were systematically classified according to clinical application, chemical compositions, pharmacological action, toxic and side effects, etc. In the analysis with traditional Chinese medicine theory, it is concluded that: C. scolymus tastes bitter and slightly cold, attributing to spleen, stomach, liver and gall meridians. It has the functions of eliminating accumulation and guiding stagnation, regulating Qi-flowing for harmonizing stomach, clearing away dampness and heat, resolving turbidity and lowering blood lipids. It can be used for the treatment of dyspepsia, diet reduction, vomiting, nausea, abdominal distention, hypochondriac pain, jaundice, hyperlipidemia, etc. Through the analysis and research of the relevant literature on C. scolymus, the properties and functions of the drug were clarified, which could provide a theoretical basis for further animal experiments and clinical research. The research model of "traditional Chinese medicine theory" for alien plant medicines can provide reference for the introduction and research of botanical drugs around the world, which can greatly enrich Chinese medicine resources and is of great significance for promoting the sustainable development of traditional Chinese medicine.

关键词(KeyWords): 朝鲜蓟;中药药性;功效;临床应用
Cynara scolymus;property of traditional Chinese medicine;efficacy;clinical application

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81874350)

作者(Author): 赵艺萌;王禅缔;张睿;侯新娟;赵凡;张建军;王淳;
ZHAO Yi-meng;WANG Chan-di;ZHANG Rui;HOU Xin-juan;ZHAO Fan;ZHANG Jian-jun;WANG Chun;College of Traditional Chinese Medicine, Beijing University of Chinese Medicine;Beijing Institute of Clinical Pharmacy;

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