中国中药杂志

2019, v.44(15) 3312-3315

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玉簪花中1个新黄酮苷类化合物及其抗氧化活性研究
A new antioxidant flavonoid glycoside from flowers of Hosta plantaginea

周庆光;杨丽;何军伟;钟国跃;
ZHOU Qing-guang;YANG Li;HE Jun-wei;ZHONG Guo-yue;Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine,Jiangxi University of Traditional Chinese Medicine;Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Traditional Chinese Medicine;

摘要(Abstract):

对蒙古族药玉簪花进行了化学成分研究。运用硅胶、凝胶及RP-HPLC等多种柱色谱从玉簪花80%乙醇提取物中分离得到1个新的黄酮苷类化合物,该化合物通过高分辨质谱、核磁共振谱等手段鉴定为玉簪黄酮苷C(1,plantanone C)。采用DPPH自由基清除活性试验对化合物1进行了体外抗氧化活性评价,结果表明化合物1显示出较强的抗氧化作用,其半数抑制浓度(IC50)为240. 2μmol·L~(-1)。
Phytochemical investigation of the flowers of Hosta plantaginea led to isolate of one new flavonoid glycoside,plantanone C( 1) by silica gel,Sephadex LH-20,and RP-HPLC column chromatographies. Its structure was extensively determined on basis of HR-ESI-MS and NMR spectroscopic data. Compound 1 exhibited moderate antioxidant activity against DPPH radical scavenging activity,with an IC50 value of 240. 2 μmol·L~(-1).

关键词(KeyWords): 蒙古族药;玉簪花;玉簪黄酮苷C;抗氧化活性
Mongolian medicine;Hosta plantaginea flowers;plantanone C;antioxidant activity

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81503357);; 江西省自然科学基金项目(20171BBH80026);; 江西省双一流学科(中药学)建设项目(JXSYLXK-ZHYAO031);; 江西省研究生创新专项资金项目(YC2017-S351)

作者(Author): 周庆光;杨丽;何军伟;钟国跃;
ZHOU Qing-guang;YANG Li;HE Jun-wei;ZHONG Guo-yue;Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine,Jiangxi University of Traditional Chinese Medicine;Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Traditional Chinese Medicine;

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