中国中药杂志

2012, v.37(02) 165-171

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灵芝三萜类化合物的研究进展
Study progress on triterpenoids from Ganoderma Lucidum

李晔;朱忠敏;姚渭溪;陈若芸;
LI Ye1,ZHU Zhongmin1,YAO Weixi1,CHEN Ruoyun2(1.Fujian Xianzhilou Biological Science & Technology Co.,Ltd.National R&D Center For Edible Fungi Processing, Fujian Engineering Research Center for Medicinal Fungi,Fuzhou 350002,China; 2.State Key Laboratory for Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China)

摘要(Abstract):

作者综述了近年来国内外有关灵芝三萜类化合物的提取纯化工艺、化学成分及含量分析的研究现状及进展。灵芝三萜类化合物是灵芝中一种重要的药用活性成分,但是由于它在灵芝中的含量低,提取和纯化工艺复杂,目前高纯度的灵芝三萜化合物的制备量小,依然处在实验室的研究规模,因此,该文进一步探讨了制备灵芝三萜类化合物的产业化技术,旨在进一步推动灵芝产业的快速发展,为其作为保健食品、药品的研究和生产提供科学依据。
In this review,recent progress in the extraction and purification,and the chemical composition analysis of triterpenoids from Ganoderma lucidum was summarized.Triterpenoids are an important class of active components in G.lucidum.Because of its low content,complex procedures of extraction and purification,the preparation of high purity triterpenoids from G.lucidum is currently limited at the laboratory scale.This review discussed the industrial preparation of triterpenoids,aiming to promote the industrial development of G.lucidum,and to provide scientific basis for its study,production,and application in health food and medicine.

关键词(KeyWords): 灵芝;三萜类化合物;提取纯化;含量分析
Ganoderma lucidum;triterpenoids;extraction;purification;analysis

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基金项目(Foundation): 科技部科技基础性工作专项重点项目(2007FY130100)

作者(Author): 李晔;朱忠敏;姚渭溪;陈若芸;
LI Ye1,ZHU Zhongmin1,YAO Weixi1,CHEN Ruoyun2(1.Fujian Xianzhilou Biological Science & Technology Co.,Ltd.National R&D Center For Edible Fungi Processing, Fujian Engineering Research Center for Medicinal Fungi,Fuzhou 350002,China; 2.State Key Laboratory for Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China)

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