中国中药杂志

2019, v.44(24) 5269-5276

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

基于知识图谱的中药制药过程质量控制方法学研究
Studies on the methodology for quality control in Chinese medicine manufacturing process based on knowledge graph

仲怿;茹晨雷;张伯礼;程翼宇;
ZHONG Yi;RU Chen-lei;ZHANG Bo-li;CHENG Yi-yu;Department of Chinese Medicine Science & Engineering,Zhejiang University;State Key Laboratory of Component Chinese Medicine,Tianjin University of Traditional Chinese Medicine;

摘要(Abstract):

根据中药制药过程质量控制技术方法的发展需求与新一代人工智能在中药工业中的现实应用场景,围绕中药制药过程质量控制方面亟待解决的核心问题,研究提出中成药生产制造知识图谱构建方法,由此设计建立适应中成药生产特点的"制药工业大脑"模型,进而创建基于知识图谱的中药制药过程质量控制方法学,并简述了中药制药知识图谱的设计方法、系统架构及主要功能。以舒血宁注射液为载体开展应用示范研究,研究建成用于舒血宁注射液智能制造的知识图谱1. 0平台,实现了中药制药过程质量控制系统从感知智能向认知智能的技术跨越。
According to the requirements for developing the quality control technology in Chinese medicine( CM) manufacturing process and the practical scenarios in applying a new generation of artificial intelligence to CM industry,we present a method of constructing the knowledge graph( KG) for CM manufacture to solve key problems about quality control in CM manufacturing process.Based on the above,a " pharmaceutical industry brain" model for CM manufacture has been established. Further,we propose founding the KG-based methodology for quality control in CM manufacturing process,and briefly describe the design method,system architecture and main functions of the KG system. In this work,the KG for manufacturing Shuxuening Injection( SXNI) was developed as a demonstration study. The KG version 1. 0 platform for intelligent manufacturing SXNI has been built,which could realize technology leap of the quality control system in CM manufacturing process from perceptual intelligence to cognitive intelligence.

关键词(KeyWords): 中药制药知识图谱;制药工业大脑;制药过程质量控制;中成药质量控制;中药智能制造
knowledge graph for Chinese medicine manufacturing;pharmaceutical industry brain;quality control in pharmaceutical manufacture process;quality control of Chinese medicine;intelligent manufacture of Chinese medicine

Abstract:

Keywords:

基金项目(Foundation): 国家食品药品监督管理总局委托研究事项资助项目

作者(Author): 仲怿;茹晨雷;张伯礼;程翼宇;
ZHONG Yi;RU Chen-lei;ZHANG Bo-li;CHENG Yi-yu;Department of Chinese Medicine Science & Engineering,Zhejiang University;State Key Laboratory of Component Chinese Medicine,Tianjin University of Traditional Chinese Medicine;

Email:

DOI:

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享