中国中药杂志

2021, v.46(19) 4881-4890

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

金丝桃属植物中多环多异戊烯基间苯三酚类成分和生物活性的研究进展
Polycyclic polyprenylated acylphloroglucinols from Hypericum species and their biological activities

宋萍;郝吉;王岩;杨新洲;
SONG Ping;HAO Ji;WANG Yan;YANG Xin-zhou;School of Chemistry and Chemical Engineering, Qinghai University for Nationalities;School of Pharmaceutical Sciences, South-Central University for Nationalities;

摘要(Abstract):

金丝桃属植物在我国广大地区均有分布,主要集中在西南地区,我国约有55种8亚种,物种类型丰富。金丝桃属植物的主要化学成分为黄酮类、氧杂蒽酮类以及间苯三酚类化合物,而间苯三酚衍生物因其结构中具有多环和多种支链取代的特征结构,所以结构类型丰富多样,同时这类成分具有抗肿瘤、抗病毒、抗菌、抗炎等生物活性。该研究对从金丝桃属植物中分离的344个多环多异戊烯基间苯三酚类化合物进行分类归纳,为金丝桃属多环多异戊烯基间苯三酚类化合物的开发和利用提供科学依据。
Hypericum species are distributed widely in China, especially in the southwest. This genus is rich in species types in China, including 55 species and 8 subspecies. The main chemical constituents of Hypericum species are flavonoids, xanthones and polycyclic polyprenylated acylphloroglucinols(PPAPs). PPAPs are characterized by polycyclic and branched-chain substitutions in their structures, which make their structure types diverse. Moreover, they have been found to have antitumor, antiviral, antibacterial, anti-inflammatory and other biological activities. This research classified and summarized 344 polycyclic polyprenylated acylphloroglucinols from Hypericum plants in order to provide a scientific basis for further development and utilization of PPAPs from the genus.

关键词(KeyWords): 金丝桃属;间苯三酚衍生物;生物活性;研究进展
Hypericum;polycyclic polyprenylated acylphloroglucinol;biological activity;research progress

Abstract:

Keywords:

基金项目(Foundation): 青海省重点研发与转化计划科技国际合作专项(2020-HZ-802);; 国家自然科学基金项目(81911540487,81774000)

作者(Authors): 宋萍;郝吉;王岩;杨新洲;
SONG Ping;HAO Ji;WANG Yan;YANG Xin-zhou;School of Chemistry and Chemical Engineering, Qinghai University for Nationalities;School of Pharmaceutical Sciences, South-Central University for Nationalities;

DOI: 10.19540/j.cnki.cjcmm.20210603.601

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享