中国中药杂志

2015, v.40(23) 4568-4572

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桂皮醛药理作用的研究进展
Research progress of trans-cinnamaldehyde pharmacological effects

张利青;张占刚;付岩;徐颖;
ZHANG Li-qing;ZHANG Zhan-gang;FU Yan;XU Ying;Department of Physiology,Shanghai University of Traditional Chinese Medicine;

摘要(Abstract):

桂皮醛是中国传统中药材桂枝或肉桂挥发油的主要成分,为烯醛类有机化合物,具有抗炎、解热镇痛、抗肿瘤、抗菌、降糖、抗肥胖和神经保护等多种药理作用。对神经系统、心血管、肿瘤、糖尿病等疾病均有一定的防治作用,作为预防保健的天然药物具有较好临床和市场潜力。该文对近5年来国内外关于桂皮醛的药理作用及其机制研究进行了综述,以期对桂皮醛的深入研究和开发提供一定的科学依据。
Trans-cinnamaldehyde,the main component of volatile oil from cassia twig or Cinnamomum cassia,which is a traditional Chinese herbal medicine. Trans-cinnamaldehyde is a kind olefine aldehyde of organic compounds and has many pharmacological properties,such as anti-inflammatory,anti-tumor,anti-bacterial,antidiabetic,anti-obesity,and neuroprotection etc. The compound has preventive and therapeutic effects on the nervous system,cardiovascular,cancer,diabetes and other diseases. Trans-cinnamaldehyde,as a preventive care of nature medicine,has great clinical and market potential. This paper gives a review about the pharmacological effects and mechanism of trans-cinnamaldehyde researched in the latest five years. We hope to provide some basic information for further research on trans-cinnamaldehyde.

关键词(KeyWords): 桂皮醛;药理作用;研究进展
trans-cinnamaldehyde;pharmacological effect;research progress

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81274119);; 上海市教育委员会科研创新项目(13YZ050);上海市教育委员会重点学科项目(J50301)

作者(Author): 张利青;张占刚;付岩;徐颖;
ZHANG Li-qing;ZHANG Zhan-gang;FU Yan;XU Ying;Department of Physiology,Shanghai University of Traditional Chinese Medicine;

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