邢旺兴,陈斌,宓鹤鸣,杨根金,吴玉田
XING Wang xing 1, CHEN Bin 2, MI He ming 2, YANG Gen jin 2, WU Yu tian 2 (1.Department of Pharmaceutical Preparations, 117th Hospital of Chinese People Liberation Army, Hangzhou 310013, China; 2.School of Pharmacy, Second Military Medical University, Shanghai 200433, China)

• 1:中国人民解放军第117医院药剂科
• 2:第二军医大学药学院
• 3:第二军医大学药学院
• 4:第二军医大学药学院

摘要(Abstract)：

目的 :研究中药通光藤Marsdeniatenacissima的化学成分。方法 :利用溶剂提取和硅胶、SephadexLH 2 0等色谱方法对云南昆明产通光藤的醋酸乙酯可溶部位进行分离纯化 ,通过化学和光谱方法鉴定结构。结果 :共分离得到 8个化合物 ,已鉴定出其中 5个化合物 :大叶牛奶菜苷丁 (Ⅰ ) ,大叶牛奶菜苷乙 (Ⅱ ) ,牛奶菜醇 (Ⅲ ) ,二氢牛奶菜醇 (Ⅳ ) ,喙柱牛奶菜苷乙 (Ⅴ )。结论 :这 5个化合物均为首次从该植物中分离得到 ;通光藤的醋酸乙酯可溶部位含有较多的甾体酯苷类化合物。
Objective: To study on the chemical constituents of Marsdenia tenacissima. Method: Compounds were separated with chromatography technology with sillica gel and Sephadex LH 20 as adsorbents, and their structures were elucidated by chemical and spectral analysis. Result: Eight compounds were isolated from Marsdenia tenacissima and the structures of five compounds among them were identified as marsdekoiside D(Ⅰ), marsdekoiside B(Ⅱ), conduritol (Ⅲ), dihydro conduritol (Ⅳ) and marsdeoreophiside B(Ⅴ). Conclusion: All these compounds were obtained from this genus for the first time.

关键词(KeyWords)： 通光藤;大叶牛奶菜苷;牛奶菜醇;喙柱牛奶菜苷
Marsdenia tenacissima; marsdekoiside; conduritol; marsdeoreophiside

Abstract:

Keywords:

基金项目(Foundation): 全军医学科研重点课题基金 (0 1Z0 64 )

作者(Author): 邢旺兴,陈斌,宓鹤鸣,杨根金,吴玉田
XING Wang xing 1, CHEN Bin 2, MI He ming 2, YANG Gen jin 2, WU Yu tian 2 (1.Department of Pharmaceutical Preparations, 117th Hospital of Chinese People Liberation Army, Hangzhou 310013, China; 2.School of Pharmacy, Second Military Medical University, Shanghai 200433, China)

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