中国中药杂志

2020, v.45(21) 5117-5128

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半枝莲化学成分、药理作用及质量控制研究进展
Research progress on chemical constituents, pharmacological action and quality control of Scutellaria barbata

李娜;王平;孙铁锋;韩莉;胡亚楠;杜海涛;刘华;
LI Na;WANG Ping;SUN Tie-feng;HAN Li;HU Ya-nan;DU Hai-tao;LIU Hua;School of Pharmacy, Shandong University of Traditional Chinese Medicine;State key Laboratory of Precision Testing Technology and Instruments, Tianjin University;Shandong Institute of Traditional Chinese Medicine;

摘要(Abstract):

半枝莲作为一种公认的抗癌中药,具有清热解毒、散瘀止血、利尿消肿之功效。目前已从半枝莲中分离得到萜类、黄酮类、多糖类以及挥发油类等化学成分,具有抗肿瘤、抗病毒、抑菌、抗氧化、免疫调节等多种药理作用。该文综述了半枝莲的化学成分、药理作用及质量控制3个方面的研究情况,以期为半枝莲的进一步开发研究提供思路与参考。
Scutellaria barbata is a recognized anti-cancer traditional Chinese medicine, with the effects of clearing heat and detoxi-fication, dispelling blood stasis and stopping bleeding, diuresis and detumescence. At present, terpenoids, flavonoids, polysaccharides and volatile oils have been isolated from S. barbata, which have many pharmacological effects, such as resisting tumor, virus, bacteria and oxidation, and immunomodulation. This paper reviews the studies on the chemical constituents, pharmacological action and quality control of S. barbata, in the expectation of providing ideas and references for the further development and studies of S. barbata.

关键词(KeyWords): 半枝莲;化学成分;药理作用;质量控制
Scutellaria barbata;chemical constituents;pharmacological action;quality control

Abstract:

Keywords:

基金项目(Foundation): 山东省重大科技创新工程项目(2018CXGC1310);; 山东省重点研发计划项目(2017CXGC1306,2016ZDJS07A23,2016GSF2020420);; 山东省自然科学基金项目(ZR2015HM061,ZR2019MH134);; 泰山学者工程项目(ts201511074);; 全国中医药创新骨干人才培养项目;; 山东省高校中药质量控制与全产业链建设协同创新中心项目(CYLXTCX2020-04)

作者(Author): 李娜;王平;孙铁锋;韩莉;胡亚楠;杜海涛;刘华;
LI Na;WANG Ping;SUN Tie-feng;HAN Li;HU Ya-nan;DU Hai-tao;LIU Hua;School of Pharmacy, Shandong University of Traditional Chinese Medicine;State key Laboratory of Precision Testing Technology and Instruments, Tianjin University;Shandong Institute of Traditional Chinese Medicine;

Email:

DOI: 10.19540/j.cnki.cjcmm.20200806.601

参考文献(References):

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